APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1-2 μg/ml |
1-2 μg/ml |
Note :
IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.
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Not tested in other applications.
Calculated MW
Observed MW
42-48 kDa. The observed M.W. is based on the following publication. PMID: 28741117|12917210
PROPERTIES
Form
Liquid
Buffer
10mM PBS, 0.05% BSA
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Concentration
200 μg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant human AMACR protein fragment (around aa 297-394)
Purification
Protein A/G purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
alpha-methylacyl-CoA racemase , AMACRD , CBAS4 , P504S , RACE , RM
Cellular Localization
Mitochondrion
Background
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]
Database
Research Area
DATA IMAGES
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GTX02585 WB Image
WB analysis of human kidney tissue lysate using GTX02585 AMACR antibody [rAMACR/1864].
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GTX02585 IHC-P Image
IHC-P analysis of human prostate carcinoma section using GTX02585 AMACR antibody [rAMACR/1864].
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GTX02585 IHC-P Image
IHC-P analysis of human prostate carcinoma section using GTX02585 AMACR antibody [rAMACR/1864].
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REFERENCE
There are currently no references for AMACR antibody [rAMACR/1864] (GTX02585). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for AMACR antibody [rAMACR/1864] (GTX02585). Be the first to share your experience with this product.