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AMACR antibody

Anti-AMACR antibody used in IHC (Paraffin sections) (IHC-P). GTX12498

Cat No. GTX12498

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
500 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:25-1:50

Note :

IHC-P
Recommendations for antigen retrieval : Citrate Buffer pH 6.0 at room temperature for 30 mins.

Not tested in other applications.

Calculated MW

42 kDa. ( Note )

Specificity/Sensitivity

This antibody can be used as a positive marker for prostatic intraepithelial neoplasia (PIN).

PROPERTIES

Form

Liquid

Buffer

PBS with <0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

A synthetic human AMACR peptide.

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

AMACR , AMACRD , CBAS4 , RACE , RM , alphamethylacylCoA racemase , p504S , alpha-methylacyl-CoA racemase

Cellular Localization

Peroxisome,Mitochondrion

Background

This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]

Database

Research Area

DATA IMAGES

Anti-AMACR antibody used in IHC (Paraffin sections) (IHC-P). GTX12498

GTX12498 IHC-P Image

IHC-P analysis of human prostate carcinoma tissue using GTX12498 AMACR antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 329