GeneTex
United States (US)

AMACR antibody

AMACR-antibody-GTX12498-IHC-1_18121409_224.jpg

Cat No. GTX12498

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application IHC-P, IHC
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

42 kDa kDa. ( Note )

Positive Control

Prostate carcinoma
PROPERTIES

Form

Liquid

Buffer

PBS, pH7.2 containing 0.05% Sodium Azide

Concentration

0.1mg/ml

Antigen Species

Human

Immunogen

Synthetic peptide (Human).

Purification

IgG fraction
Purified immunoglobulin fraction of rabbit antiserum

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

AMACR, 604489, 23600, RACE, Q9UHK6

Cellular Localization

Mitochondrial and Peroxisomal.

Background

AMARC has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMARC protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. P504S can be used as a positive marker for PIN.
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Database

Research Area

DATA IMAGES
AMACR-antibody-GTX12498-IHC-1_18121409_224.jpg

GTX12498 IHC Image

IHC Image using GTX12498 - Detection of AMACR by IHC in Human Tonsil