AMOTL2 antibody [N3C2], Internal

Name: AMOTL2 antibody [N3C2], Internal
Brand: GeneTex
SKU: GTX120712
Price: 399.00 USD
Rating: 4 (1 reviews)

Anti-AMOTL2 antibody [N3C2], Internal used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX120712

Cat. No. GTX120712

Reference 3

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	ICC/IF, IHC
Reactivity	Human, Mouse, Dog
Package	100 μl ($399), 25 μl ($169)

See all AMOTL2 products

View product citations for antibody GTX120712 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
ICC/IF	Assay dependent
IHC	Assay dependent

Not tested in other applications.

Calculated MW

86 kDa. ( Note )

Predict Reactivity

Rat(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.02 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human AMOTL2. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_11178591

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

angiomotin like 2 , LCCP

Background

Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motins protein family. [provided by RefSeq]

Database

Gene ID: 51421 AMOTL2
UniProt: Q9Y2J4 AMOTL2

Research Area

DATA IMAGES

GTX120712 ICC/IF Image

The data was published in the journal Sci Rep in 2017.PMID: 28842668

REFERENCE

Application Reference

Eder N et al. Nat Commun 2020; 11 (1) : 2380 YAP1/TAZ drives ependymoma-like tumour formation in mice.

Application : IHC

Reactivity : Mouse

Hildebrand S et al. Sci Rep 2017; 7 (1) : 9540 The E-cadherin/AmotL2 complex organizes actin filaments required for epithelial hexagonal packing and blastocyst hatching.

Application : ICC/IF

Reactivity : Human

Proszynski TJ et al. J Cell Sci 2013; 126 (Pt 10) : 2225-35 Amotl2 interacts with LL5β, localizes to podosomes and regulates postsynaptic differentiation in muscle.

Application : ICC/IF

Reactivity : Mouse

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