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AMPD3 antibody [AMPD3/901]

Anti-AMPD3 antibody [AMPD3/901] used in IHC (Paraffin sections) (IHC-P). GTX34411
Anti-AMPD3 antibody [AMPD3/901] used in IHC (Paraffin sections) (IHC-P). GTX34411

Cat. No. GTX34411

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 AMPD3/901

Isotype

 IgG2b

Application

 IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all AMPD3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 2-4μg/ml for 30 minutes at RT

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

89 kDa. ( Note )

Product Note

This antibody recognizes a protein of ~90kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human AMDP3 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

AMPD3 , adenosine monophosphate deaminase 3

Background

This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-AMPD3 antibody [AMPD3/901] used in IHC (Paraffin sections) (IHC-P). GTX34411

GTX34411 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX34411 AMPD3 antibody [AMPD3/901].

Anti-AMPD3 antibody [AMPD3/901] used in IHC (Paraffin sections) (IHC-P). GTX34411

GTX34411 IHC-P Image

IHC-P analysis of human placenta tissue using GTX34411 AMPD3 antibody [AMPD3/901].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529