GeneTex
United States (US)

ANTXR2 antibody, Internal

GTX88121_1053_IHC-P_18122102_444.jpg
GTX88121_2515_WB_18122102_769.jpg
GTX88121_1054_IHC-P_18122102_807.jpg

Cat No. GTX88121

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.3-1μg/ml
IHC-P 2.5μg/ml
Not tested in other applications.

Calculated MW

54 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88121-PEP).

Specificity/Sensitivity

This antibody is expected to recognize both reported isoforms (NP_477520.2; NP_001139266.1).

Predict Reactivity

Rat, Bovine, Dog(>80% identity)
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-HEGLKLANEQIQK, from the internal regoin of the protein sequence according to NP_477520.2; NP_001139266.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Antxr Cell Adhesion Molecule 2,Cmg-2,Cmg2,Hfs,Ish,Jhf,Antxr2

Cellular Localization

Expressed at the cell surface. Expressed predominantly within the endoplasmic reticulum and not at the plasma membrane.

Background

This gene encodes a receptor for anthrax toxin. The protein binds to collagen IV and laminin, suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Database

DATA IMAGES
GTX88121_1053_IHC-P_18122102_444.jpg

GTX88121 IHC-P Image

IHC-P analysis of human kidney using GTX88121 ANTXR2 antibody, Internal.
Antigen retrieval : citrate buffer pH 6
Dilution : 2.5µg/ml

GTX88121_2515_WB_18122102_769.jpg

GTX88121 WB Image

WB analysis of mouse kidney lysate using GTX88121 ANTXR2 antibody, Internal.
Dilution : 0.3µg/ml
Loading : 35µg protein in RIPA buffer

GTX88121_1054_IHC-P_18122102_807.jpg

GTX88121 IHC-P Image

IHC-P analysis of human liver using GTX88121 ANTXR2 antibody, Internal.
Antigen retrieval : citrate buffer pH 6
Dilution : 2.5µg/ml

Package List Price ($)
$ 329