GeneTex
United States (US)

AP3M1 antibody

GTX32019_1703_IHC-P_20180221_18121410_686.jpg
GTX32019_3151_WB_20180221_18121410_557.jpg
GTX32019_1702_IHC-P_20180221_18121410_162.jpg

Cat No. GTX32019

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

47 kDa. ( Note )

Positive Control

Human Brain Tissue Lysate(GTX27918)

Specificity/Sensitivity

AP3M1 antibody may cross-react with AP3M2.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

AP3M1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human AP3M1.The immunogen is located within amino acids 340 - 390 of AP3M1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Adaptor Related Protein Complex 3 Subunit Mu 1,Ap3M1

Background

The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane and may be directly involved in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX32019_1703_IHC-P_20180221_18121410_686.jpg

GTX32019 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX32019 AP3M1 antibody.
Working concentration : 20 μg/ml

GTX32019_3151_WB_20180221_18121410_557.jpg

GTX32019 WB Image

WB analysis of human brain tissue lysate using GTX32019 AP3M1 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

GTX32019_1702_IHC-P_20180221_18121410_162.jpg

GTX32019 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX32019 AP3M1 antibody.
Working concentration : 5 μg/ml

Package List Price ($)
$ 329