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APC5 antibody

Anti-APC5 antibody used in IHC (Paraffin sections) (IHC-P). GTX33008
Anti-APC5 antibody used in Western Blot (WB). GTX33008
Anti-APC5 antibody used in IHC (Paraffin sections) (IHC-P). GTX33008

Cat No. GTX33008

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

85 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ANAPC5 (NP_057321.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

anaphase promoting complex subunit 5 , APC5

Background

This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008]

Database

Research Area

DATA IMAGES

Anti-APC5 antibody used in IHC (Paraffin sections) (IHC-P). GTX33008

GTX33008 IHC-P Image

IHC-P analysis of human kidney tissue using GTX33008 ANAPC5 antibody.
Dilution : 1:100

Anti-APC5 antibody used in Western Blot (WB). GTX33008

GTX33008 WB Image

WB analysis of various samples using GTX33008 ANAPC5 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-APC5 antibody used in IHC (Paraffin sections) (IHC-P). GTX33008

GTX33008 IHC-P Image

IHC-P analysis of rat kidney tissue using GTX33008 ANAPC5 antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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Package List Price ($)
$ 329