*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
HepG2, HeLa, Raji whole cell lysates
Phosphate-buffered saline, pH 7.2, no preservatives added
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Full length human APE1 purified from E. coli
Protein G purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Apurinic/Apyrimidinic Endodeoxyribonuclease 1 , Ape , Ape1 , Apen , Apex , Apx , Hap1 , Ref1 , Apex1
Apurinic / Apyrimidinic Endonuclease (APE 1 or REF 1) is responsible for the incision of DNA at abasicsites during base excision repair. It has also been shown to stimulate the sequence-specific DNA binding activity of Fos-Jun (AP 1) heterodimers. Alterations in APE 1 levels have been described insome cancers.