For WB: Use at a dilution of 1:2,500. Predicted molecular weight: 38 kDa. Optimal dilutions/concentrations should be determined by the researcher.
HeLa, Raji whole cell lysates
Antiserum containing no preservatives
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Full length human APE1 purified from E. coli
From polyclonal serum
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Apurinic/Apyrimidinic Endodeoxyribonuclease 1 , Ape , Ape1 , Apen , Apex , Apx , Hap1 , Ref1 , Apex1
Apurinic / Apyrimidinic Endonuclease (APE 1 or REF 1) is responsible for the incision of DNA at abasicsites during base excision repair. It has also been shown to stimulate the sequence-specific DNA binding activity of Fos-Jun (AP 1) heterodimers. Alterations in APE 1 levels have been described insome cancers.