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APE1 antibody

Anti-APE1 antibody used in Western Blot (WB). GTX70129

Cat No. GTX70129

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB

Reactivity

Human, Mouse
Package
100 μl ($329)

APPLICATION

Application Note

For WB: Use at a dilution of 1:2,500. Predicted molecular weight: 38 kDa. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

36 kDa. ( Note )

Positive Control

HeLa, Raji whole cell lysates

PROPERTIES

Form

Liquid

Buffer

Antiserum containing no preservatives

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Full length human APE1 purified from E. coli

Purification

Unpurified
From polyclonal serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Apurinic/Apyrimidinic Endodeoxyribonuclease 1 , Ape , Ape1 , Apen , Apex , Apx , Hap1 , Ref1 , Apex1

Background

Apurinic / Apyrimidinic Endonuclease (APE 1 or REF 1) is responsible for the incision of DNA at abasicsites during base excision repair. It has also been shown to stimulate the sequence-specific DNA binding activity of Fos-Jun (AP 1) heterodimers. Alterations in APE 1 levels have been described insome cancers.

Database

Research Area

DATA IMAGES

Anti-APE1 antibody used in Western Blot (WB). GTX70129

GTX70129 WB Image

GTX70129 at a 1:2500 dilution staining APE / REF 1 in A) HeLa whole cell lysate and B) Raji whole cell lysate in Western Blot (ECL).

REFERENCE

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REVIEW

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Package List Price ($)
$ 329