0.001% Na2HPO4, 0.025% BSA, 0.0045% NaCl, 0.00025% Thimerosal, 0.00025% NaN3
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.
A synthetic peptide corresponding to a sequence at the C-terminus of human API5 (487-504aa KYSSNLGNFNYERSLQGK)(b), different from the related mouse sequence by one amino acid.
Purified by antigen-affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Apoptosis Inhibitor 5,Aac-11,Aac11,Api5
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]