GeneTex
United States (US)

APP antibody [3E9]

Amyloid-Precursor-Protein-antibody-3E9_WB_GTX12338-1_18121409_235.jpg

Cat No. GTX12338

Host Mouse
Clonality Monoclonal
Clone Name 3E9
Isotype IgG1
Application WB, IHC-P
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

87 kDa kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Preservative: NoneConstituents: PBS, 10mg/ml Sucrose

Concentration

1mg/ml

Antigen Species

Human

Immunogen

Synthetic peptide: LEVPTDGNAGLLAEPQIAMFC , corresponding to amino acids 18-38 of Human Amyloid Precursor Protein.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

AD1, APP, ABETA, CTFgamma, APPI, 351, ABPP, Amyloid Precursor Protein, CVAP, PN2, 104760, P05067, AAA

Cellular Localization

Endoplasmic reticulum, Golgi Apparatus, Cytoplasmic, Cell Membrane.

Background

Amyloid Precursor Protein (APP) functions as a cell surface kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1; APP is rapidly internalized via clathrin-coated pits. APP is important for neurite growth, neuronal adhesion and axonogenesis.
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Database

Research Area

DATA IMAGES
Amyloid-Precursor-Protein-antibody-3E9_WB_GTX12338-1_18121409_235.jpg

GTX12338 WB Image

Western blot analysis of Amyloid Precursor Protein expression in mouse brain using APP mAb (3E9)