APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:500-1:3000 |
1:100-1:1000 |
1:100-1:1000 |
Not tested in other applications.
Calculated MW
Positive Control
Jurkat
Predict Reactivity
Mouse, Rat, Zebrafish, Chicken, Rhesus Monkey(>80% identity)
PROPERTIES
Form
Liquid
Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol
Preservative
0.01% Thimerosal
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.44 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant protein encompassing a sequence within the center region of human APPBP2. The exact sequence is proprietary.
Purification
Purified by antigen-affinity chromatography.
Conjugation
Unconjugated
RRID
AB_10618843
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
amyloid beta precursor protein binding protein 2 , APP-BP2 , HS.84084 , PAT1
Cellular Localization
Nucleus , Cytoplasm , cytoskeleton , Membrane; Peripheral membrane protein , Nucleus , Cytoplasm , cytoskeleton , Membrane
Background
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. [provided by RefSeq]
Database
Research Area
DATA IMAGES
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GTX117735 WB Image
Sample (30 ug of whole cell lysate) A: Jurkat 7.5% SDS PAGE GTX117735 diluted at 1:1000
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GTX117735 ICC/IF Image
Immunofluorescence analysis of methanol-fixed HeLa, using APPBP2(GTX117735) antibody at 1:100 dilution.
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GTX117735 IHC-P Image
Immunohistochemical analysis of paraffin-embedded Ca922 xenograft, using APPBP2(GTX117735) antibody at 1:100 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min
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REFERENCE
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REVIEW
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