APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
0.5 - 1 μg/mL |
5 μg/mL |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Human Brain Tissue Slide(GTX22203) , Human Brain Tissue Lysate(GTX27918)
Product Note
At least two isoforms are known to exist; this antibody will detect both isoforms.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
APPBP2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human APPBP2.The immunogen is located within the last 50 amino acids of APPBP2.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
amyloid beta precursor protein binding protein 2 , APP-BP2 , HS.84084 , PAT1
Cellular Localization
Nucleus,Cytoplasm, cytoskeleton,Membrane
Background
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX31561 IHC-P Image
IHC-P analysis of human brain tissue using GTX31561 APPBP2 antibody. Working concentration : 5 μg/ml
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GTX31561 WB Image
WB analysis of human brain tissue lysate using GTX31561 APPBP2 antibody. Working concentration : (A) 0.5 and (B) 1 μg/ml
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GTX31561 IHC-P Image
IHC-P analysis of human brain tissue using GTX31561 APPBP2 antibody. Working concentration : 20 μg/ml
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REFERENCE
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REVIEW
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