*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
U87-MG , MCF-7
Zebrafish, Bovine, Pig, Xenopus laevis(>80% identity)
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.)
Recombinant protein encompassing a sequence within the N-terminus region of human APPL1. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
APPL antibody, DIP13alpha antibody, APPL1 antibody, DCC-interacting protein 13-alpha antibody, "adaptor protein containing pH domain, PTB domain and leucine zipper motif 1 antibody", "adapter protein containing PH domain, PTB domain and leucine zipper motif 1 antibody", AKT2 interactor antibody, signaling adaptor protein DIP13alpha antibody, dip13-alpha antibody, "adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 antibody"
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq]