GeneTex

  • Country / Location Selection

United States (US)

APRIL antibody [Aprily-1]

Cat. No. GTX16088

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 Aprily-1

Isotype

 IgG1

Application

 WB, FACS

Reactivity

 Human
Package
50 μg ($399)
See all APRIL products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 2 μg/mL
FACS 10 μg/mL

Note :

FACS
HEK 293T cells (5 x 10⁵) were mock transfected or transfected with human APRIL.
Not tested in other applications.

Calculated MW

27 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

APRIL (monoclonal Aprily-1) antibody was raised against recombinant human APRIL (aa. 93-233).

Purification

Purified IgG1

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TNF superfamily member 13 , APRIL , CD256 , TALL-2 , TALL2 , TNLG7B , TRDL-1 , UNQ383/PRO715 , ZTNF2

Cellular Localization

Secreted

Background

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.

Database

Research Area

REFERENCE

There are currently no references for APRIL antibody [Aprily-1] (GTX16088). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for APRIL antibody [Aprily-1] (GTX16088). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399