GeneTex
United States (US)

APRIL antibody [Aprily-1]

Cat No. GTX16088

Host Mouse
Clonality Monoclonal
Clone Name Aprily-1
Isotype IgG1
Application WB, FACS
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 2 μg/mL
FACS 10 μg/mL

Note :

FACS
HEK 293T cells (5 x 10?) were mock transfected or transfected with human APRIL.

Not tested in other applications.

Calculated MW

27 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

APRIL (monoclonal Aprily-1) antibody was raised against recombinant human APRIL (aa. 93-233).

Purification

Purified IgG1

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Tnf Superfamily Member 13,April,Cd256,Tall-2,Tall2,Tnlg7B,Trdl-1,Unq383/Pro715,Ztnf2,Tnfsf13

Background

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.

Database

Package List Price ($)
$ 329