APPLICATION
Application Note
For FACS: Use at a concentration of 1 μg/ml. For ICC: Use at a concentration of 5 μg/ml. Optimal dilutions/concentrations should be determined by the researcher.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant human APRIL (aa 105-250) fused to human ACRP30headless (aa 16-108)
Purification
>95% by SDS-PAGE
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
TNF superfamily member 13 , APRIL , CD256 , TALL-2 , TALL2 , TNLG7B , TRDL-1 , UNQ383/PRO715 , ZTNF2
Cellular Localization
Secreted
Background
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]
Database
Research Area
DATA IMAGES
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GTX16085 FACS Image
Monoclonal antibody to APRIL (GTX16085) detects membrane-bound human APRIL by FACS
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GTX16085 IHC Image
Immunostaining of HEK-293T cells transfected with a mouse APRIL expression plasmid (left panels) or mock transfected (right panel)
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REFERENCE
There are currently no references for APRIL antibody [Sacha-1] (GTX16085). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for APRIL antibody [Sacha-1] (GTX16085). Be the first to share your experience with this product.