APRIL antibody [Sacha-1]

Cat No. GTX16085

Host	Rat
Clonality	Monoclonal
Clone Name	Sacha-1
Isotype	IgG2a
Application	ICC/IF, FACS, IHC
Reactivity	Human, Mouse
Package	50 μg ($329)

See all APRIL products

Datasheet
Document

APPLICATION

Application Note

For FACS: Use at a concentration of 1 μg/ml. For ICC: Use at a concentration of 5 μg/ml. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

27 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human APRIL (aa 105-250) fused to human ACRP30headless (aa 16-108)

Purification

>95% by SDS-PAGE

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

TNF superfamily member 13 , APRIL , CD256 , TALL-2 , TALL2 , TNLG7B , TRDL-1 , UNQ383/PRO715 , ZTNF2

Cellular Localization

Secreted

Background

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]

Database

Gene ID: 8741 TNFSF13
UniProt: O75888 TNFSF13

Research Area

DATA IMAGES

GTX16085 FACS Image

Monoclonal antibody to APRIL (GTX16085) detects membrane-bound human APRIL by FACS

GTX16085 IHC Image

Immunostaining of HEK-293T cells transfected with a mouse APRIL expression plasmid (left panels) or mock transfected (right panel)

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf

Package

List Price ($)

50 μg

$ 329

Qty

APRIL antibody [Sacha-1]

Cat No. GTX16085

Host

Clonality

Clone Name

Isotype

Application

Reactivity