GeneTex
United States (US)

ARHGEF11 antibody

GTX16242_685_IHC-P_20180221_18121410_678.jpg

Cat No. GTX16242

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat, Bovine, Dog, Chicken, Monkey, Chimpanzee, Horse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 5 μg/mL
IHC-P 5 μg/mL
Not tested in other applications.

Calculated MW

168 kDa. ( Note )

Specificity/Sensitivity

A portion of amino acids 1-50 of human ARHGEF11.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.2% gelatin, 0.05% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A portion of amino acids 1-50 of human ARHGEF11.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Rho Guanine Nucleotide Exchange Factor 11,Gtrap48,Pdz-Rhogef,Arhgef11

Background

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
GTX16242_685_IHC-P_20180221_18121410_678.jpg

GTX16242 IHC-P Image

IHC-P analysis of human skin tissue using GTX16242 ARHGEF11 antibody.

Package List Price ($)
$ 579