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ARHGEF9 antibody

Anti-ARHGEF9 antibody used in Western Blot (WB). GTX33018
Anti-ARHGEF9 antibody used in IHC (Paraffin sections) (IHC-P). GTX33018
Anti-ARHGEF9 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33018

Cat No. GTX33018

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-P

Reactivity

Human, Mouse
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:100
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

61 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 307-516 of human ARHGEF9 (NP_056000.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Cdc42 guanine nucleotide exchange factor 9 , COLLYBISTIN , EIEE8 , HPEM-2 , PEM-2 , PEM2

Cellular Localization

Cytoplasm

Background

The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. This brain-specific protein also acts as an adaptor protein for the recruitment of gephyrin and together these proteins facilitate receceptor recruitement in GABAnergic and glycinergic synapses. Defects in this gene are the cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy, as well as several other types of cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]

Database

DATA IMAGES

Anti-ARHGEF9 antibody used in Western Blot (WB). GTX33018

GTX33018 WB Image

WB analysis of various samples using GTX33018 ARHGEF9 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-ARHGEF9 antibody used in IHC (Paraffin sections) (IHC-P). GTX33018

GTX33018 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX33018 ARHGEF9 antibody.
Dilution : 1:100

Anti-ARHGEF9 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33018

GTX33018 ICC/IF Image

ICC/IF analysis of A549 cell using GTX33018 ARHGEF9 antibody.
Blue : DAPI

REFERENCE

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REVIEW

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Package List Price ($)
$ 329