APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1 - 2 μg/mL |
2.5 μg/mL |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Human Brain Tissue Slide(GTX22203) , Mouse Brain Tissue Lysate(GTX27934)
Product Note
This antibody does not cross-react with CDNF.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
ARMET antibody was raised against a 12 amino acid synthetic peptide from near the carboxy terminus of human ARMET.The immunogen is located within the last 50 amino acids of ARMET.
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
mesencephalic astrocyte derived neurotrophic factor , ARMET , ARP
Cellular Localization
Secreted
Background
The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related. [provided by RefSeq, Jun 2010]
Database
Research Area
DATA IMAGES
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GTX31324 WB Image
WB analysis of mouse brain tissue lysate using GTX31324 ARMET antibody. Working concentration : (A) 1 and (B) 2 μg/ml
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GTX31324 IHC-P Image
IHC-P analysis of human brain tissue using GTX31324 ARMET antibody. Working concentration : 2.5 μg/ml
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GTX31324 IHC-P Image
IHC-P analysis of human brain tissue using GTX31324 ARMET antibody. Working concentration : 20 μg/ml
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GTX31324 IHC-P Image
IHC-P analysis of human brain tissue using GTX31324 ARMET antibody. Working concentration : 2.5 μg/ml
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GTX31324 WB Image
WB analysis of HEK293T cell or ARMET KO cell lysates using GTX31324 ARMET antibody. Dilution : 1μg/mL Loading : 10μg
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REFERENCE
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REVIEW
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