Western blot at 0.5 to 2 μg/ml. Human lung, kidney and spleen tissue lysates can be used as a positive control and a band at 32 kDa can be detected.
Human lung, kidney and spleen tissue lysates.
PBS with 0.02% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1mg/ml(Please refer to the vial label for the specific concentration.)
Synthetic peptide: KRFLEDTTDDGE, corresponding to amino acids 3-14 of Human ARTS.
Immunogen affinity purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
hCDCREL2, 603696, hCDCREL-2, H5, hucep-7, 5414, ARTS, O43236, hucep7, SEPT4, PNUTL2, CE5B3, hucep 7, hCDCREL 2
Mitochondrial and Nuclear
Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-b signaling pathway (1). ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene (1-4) is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-b and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand.
GTX29651 IHC-P Image
Immunohistochemical staining of ARTS in human lung tissue with ARTS antibody (GTX29651) at 2μg/ml.
GTX29651 WB Image
Western blot analysis of ARTS expression in human lung (lane 1),spleen (lane 2), and kidney (lane 3) tissue lysates with ARTS antibody (GTX29651) at 2μg /ml.