GeneTex

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United States (US)

ARTS peptide

Cat. No. GTX29652

Application

 Neutralizing/Inhibition

Species

 Human
Package
50 μg ($139)
See all ARTS products

APPLICATION

Application Note

The peptide is used for blocking the activity of anit-ARTS antibody (GTX29651). Incubatingthe peptide with equal volume of antibody for 30 min at 37ºC usually completely blocks theactivity of anti-ARTS in Western blotting.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.02% Sodium azide

Storage

Store the peptide at -20ºC, stable for one year.

Concentration

0.20 mg/ml (Please refer to the vial label for the specific concentration.)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Septin 4 , Arts , Bradeion , Ce5B3 , H5 , Mart , Pnutl2 , Sep4 , Hcdcrel-2 , Hucep-7 , Sept4

Background

Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-b signaling pathway (1). ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene (1-4) is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-b and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand.

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 139