APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500-1:3000 |
| 1:100-1:1000 |
Not tested in other applications.
Calculated MW
Positive Control
A549
Predict Reactivity
Mouse, Rat, Bovine, Chimpanzee, Rhesus Monkey(>80% identity)
PROPERTIES
Form
Liquid
Buffer
0.1M Tris-Glycine (pH7), 20% Glycerol
Preservative
0.01% Thimerosal
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.94 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant protein encompassing a sequence within the center region of human ASC1. The exact sequence is proprietary.
Purification
Purified by antigen-affinity chromatography.
Conjugation
Unconjugated
RRID
AB_11167229
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
thyroid hormone receptor interactor 4 , ASC-1 , ASC1 , HsT17391 , MDCDC , SMABF1 , ZC2HC5
Cellular Localization
Nucleus , Cytoplasm
Background
Transcription coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. Plays a role in androgen receptor transactivation and in testicular function.
Database
Research Area
DATA IMAGES
![Anti-ASC1 antibody [N1C1] used in IHC (Paraffin sections) (IHC-P). GTX119681](/templates/default/js/lightbox/images/loading.gif "Anti-ASC1 antibody [N1C1] used in IHC (Paraffin sections) (IHC-P). GTX119681")
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GTX119681 IHC-P Image
Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using ASC1(GTX119681) antibody at 1:250 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min
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GTX119681 WB Image
Sample (30 ug of whole cell lysate)
A: A549
7.5% SDS PAGE
GTX119681 diluted at 1:1000
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REFERENCE
There are currently no references for ASC1 antibody [N1C1] (GTX119681). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for ASC1 antibody [N1C1] (GTX119681). Be the first to share your experience with this product.
![Anti-ASC1 antibody [N1C1] used in IHC (Paraffin sections) (IHC-P). GTX119681](/upload/website/prouct_img/small/GTX119681/GTX119681_40548_IHC_18121410_543.jpg "Anti-ASC1 antibody [N1C1] used in IHC (Paraffin sections) (IHC-P). GTX119681")
![Anti-ASC1 antibody [N1C1] used in Western Blot (WB). GTX119681](/upload/website/prouct_img/small/GTX119681/GTX119681_40548_WB_18121410_229.jpg "Anti-ASC1 antibody [N1C1] used in Western Blot (WB). GTX119681")
![Anti-ASC1 antibody [N1C1] used in IHC (Paraffin sections) (IHC-P). GTX119681](/upload/website/prouct_img/normal/GTX119681/GTX119681_40548_IHC_18121410_543.jpg "Anti-ASC1 antibody [N1C1] used in IHC (Paraffin sections) (IHC-P). GTX119681")
![Anti-ASC1 antibody [N1C1] used in Western Blot (WB). GTX119681](/upload/website/prouct_img/normal/GTX119681/GTX119681_40548_WB_18121410_229.jpg "Anti-ASC1 antibody [N1C1] used in Western Blot (WB). GTX119681")