GeneTex
United States (US)

ASM antibody

GTX64562_20180530_WB_18121411_176.jpg
GTX64562_20180530_ICCIF_18121411_325.jpg

Cat No. GTX64562

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:10 - 1:100
Not tested in other applications.

Calculated MW

70 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 70-340 of human SMPD1 (NP_000534.3).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

ASMASE Antibody , SMPD1 Antibody , NPD Antibody

Background

The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010]

Database

Research Area

DATA IMAGES
GTX64562_20180530_WB_18121411_176.jpg

GTX64562 WB Image

WB analysis of various samples using GTX64562 ASM antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX64562_20180530_ICCIF_18121411_325.jpg

GTX64562 ICC/IF Image

ICC/IF analysis of HeLa cell using GTX64562 ASM antibody.
Blue : DAPI

Package List Price ($)
$ 319