GeneTex
United States (US)

ATF2 antibody

GTX100224_39274_IHC_19011506_628.jpg

Cat No. GTX100224

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

55 kDa. ( Note )

Predict Reactivity

Bovine, Chimpanzee(>80% identity)
PROPERTIES

Form

Liquid

Buffer

1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ATF2. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

CRE-BP1 antibody, CREB2 antibody, HB16 antibody, MGC111558 antibody, TREB7 antibody, ATF2 antibody, CREB-2 antibody, cAMP-dependent transcription factor ATF-2 antibody, cyclic AMP-responsive element-binding protein 2 antibody, cAMP response element-binding protein CRE-BP1 antibody, cAMP-responsive element-binding protein 2 antibody, cyclic AMP-dependent transcription factor ATF-2 antibody, "cAMP responsive element binding protein 2, formerly antibody", activating transcription factor 2 splice variant ATF2-var2 antibody, activating transcription factor 2 antibody

Cellular Localization

Nucleus

Background

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX100224_39274_IHC_19011506_628.jpg

GTX100224 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human breast cancer, using ATF2(GTX100224) antibody at 1:250 dilution.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169