GeneTex
United States (US)

ATP7b antibody

GTX30077_20180530_ICCIF_18121410_340.jpg
GTX30077_20180530_WB_18121410_887.jpg

Cat No. GTX30077

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

157 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1055-1354 of human ATP7B (NP_001230111.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Atpase Copper Transporting Beta,Pwd,Wc1,Wd,Wnd,Atp7B

Background

This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX30077_20180530_ICCIF_18121410_340.jpg

GTX30077 ICC/IF Image

ICC/IF analysis of U2OS cell using GTX30077 ATP7b antibody.
Blue : DAPI

GTX30077_20180530_WB_18121410_887.jpg

GTX30077 WB Image

WB analysis of various samples using GTX30077 ATP7b antibody.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 319