PBS, 0.02% Sodium Azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
1 mg/ml (Please refer to the vial label for the specific concentration.)
A synthetic peptide made to an internal sequence near the N-terminus of human ATP7b. [UniProt# P35670]
Purified by antigen-affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Atpase Copper Transporting Beta,Pwd,Wc1,Wd,Wnd,Atp7B
Golgi apparatus,trans-Golgi network membrane, Multi-pass membrane protein,Isoform 2: Cytoplasm,WND/140 kDa: Mitochondrion,Golgi apparatus,trans-Golgi network membrane,Isoform 2: Cytoplasm,WND/140 kDa: Mitochondrion
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). [provided by RefSeq]