0.1 ml Tris-citrate/phosphate, pH 7-8, with 0.1% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
1.0 mg/ml (Please refer to the vial label for the specific concentration.)
Immunogen was a synthetic peptide, which represented a portion of human ATR and Rad3 related encoded within exon 29 (LocusLink ID 545).
Affinity purified with antigen
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Atr Serine/Threonine Kinase,Fctcs,Frp1,Mec1,Sckl,Sckl1,Atr
Type I membrane protein (Probable).
Ataxia Telangiectasia Mutated (ATM) and Rad 3-related protein (ATR) is a phosphatidylinositol kinase (PK)-related kinase which functions in response to DNA damage and repair as well as at DNA replication checkpoints during the cell cycle. ATR is a member of the DNA-PK kinases closely related to ATM and DNA-PK for which DNA stimulates the observed kinase activity. Chromosomal remodeling proteins have also been reported to associate with ATR complexes. Several known components of the NuRD complex including histone deacetylase 1 (HDAC1), HDAC2, and CHD4.