ATR antibody
Cat. No. GTX128146
Cat. No. GTX128146
This ATR antibody (GTX128146) is a rabbit polyclonal antibody validated for detection of ATR by WB, ICC/IF, IHC-P, and IP. Reactivity has been shown in Human and Mouse. This product is cited in 12 published studies. Knockout/knockdown validation supports antibody specificity.
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HostRabbit
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ClonalityPolyclonal
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IsotypeIgG
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ApplicationsWB ICC/IF IHC-P IP
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ReactivityHuman, Mouse
Summary
ATR antibody detects the serine/threonine-protein kinase ATR (Ataxia Telangiectasia and Rad3-related protein) (also known as FRAP-related protein 1 (FRP1)). ATR (301 kDa) is a key component of the DNA damage response machinery and is activated by ssDNA, leading to cell cycle arrest while DNA damage is repaired. It also plays a critical role in stabilizing the genome during DNA replication by preventing premature onset of mitosis. This ATR antibody is a cited rabbit polyclonal validated for multiple applications.