GeneTex
United States (US)

AVPR1B antibody, C-term

GTX88639_2199_WB_18121411_423.jpg
GTX88639_884_IHC-P_18121411_287.jpg

Cat No. GTX88639

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.05-0.2μg/ml
IHC-P 5-10μg/ml

Note :

Human Pituitary shows bright cytoplasm staining of a few active secretory cells in the anterior pituitary.
Not tested in other applications.

Calculated MW

47 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88639-PEP).
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Concentration

0.50mg/ml

Antigen Species

Human

Immunogen

Peptide with sequence C-PRDLELADGEGTAE, from the C Terminus of the protein sequence according to NP_000698.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

AVPR3 Antibody

Background

The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008]
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Database

DATA IMAGES
GTX88639_2199_WB_18121411_423.jpg

GTX88639 WB Image

WB analysis of A) human amygdala lysate, B) Rat brain lysate using GTX88639 AVPR1B antibody, C-term.
Dilution : 0.5µg/ml
Loading : 35µg protein in RIPA buffer

GTX88639_884_IHC-P_18121411_287.jpg

GTX88639 IHC-P Image

IHC-P analysis of human anterior pituitary gland using GTX88639 AVPR1B antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 5µg/ml

Package List Price ($)
$ 329