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AXIN1 antibody, C-term

Anti-AXIN1 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89836

Cat No. GTX89836

Host

Goat

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
100 μg ($369)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 3-5μg/ml

Note :

IHC-P
Human Adrenal Gland shows membranous and fibrous staniing in and around secretory cells of the zona fasciculata in the cortex.

Not tested in other applications.

Calculated MW

96 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX89836-PEP).

Product Note

This antibody is expected to recognise both reported isoforms.

Predict Reactivity

Mouse, Rat, Bovine, Dog(>80% identity)

PROPERTIES

Form

Liquid

Buffer

TBS pH7.3, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-FEEKIIGKVEKVD, from the C Terminus of the protein sequence according to NP_003493.1; NP_851393.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

axin 1 , AXIN , PPP1R49

Cellular Localization

Cytoplasm , Nucleus , Membrane , Cell membrane

Background

This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Database

Research Area

DATA IMAGES

Anti-AXIN1 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89836

GTX89836 IHC-P Image

IHC-P analysis of human adrenal cortex using GTX89836 AXIN1 antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 3.8μg/ml

REFERENCE

There are currently no references for AXIN1 antibody, C-term (GTX89836). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for AXIN1 antibody, C-term (GTX89836). Be the first to share your experience with this product.
SDS
Sodium Azide.pdf
Package List Price ($)
$ 369