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Acetyl-CoA Carboxylase 1 antibody [RM232]

Anti-Acetyl-CoA Carboxylase 1 antibody [RM232] used in Western Blot (WB). GTX33608
Anti-Acetyl-CoA Carboxylase 1 antibody [RM232] used in IHC (Paraffin sections) (IHC-P). GTX33608

Cat No. GTX33608

Host

Rabbit

Clonality

Monoclonal

Clone Name

RM232

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000 - 1:2000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

266 kDa. ( Note )

Predict Reactivity

Mouse, Rat(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 0.09% sodium azide, 50% Glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A peptide corresponding to human Acetyl CoA Carboxylase 1.

Purification

Protein A purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ACAC,ACACA,ACACAD,ACC,ACC1,ACCA,acetylCoA carboxylase alpha,Acetyl-CoA Carboxylase 1,Acetyl-CoA Carboxylase alpha,acetyl-CoA carboxylase alpha

Cellular Localization

Cytoplasm

Background

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

  • Gene ID: 31 ACACA
  • UniProt: Q13085 ACACA

Research Area

DATA IMAGES

Anti-Acetyl-CoA Carboxylase 1 antibody [RM232] used in Western Blot (WB). GTX33608

GTX33608 WB Image

WB analysis of A431 cell lysates using GTX33608 Acetyl-CoA Carboxylase 1 antibody [RM232].
Dilution : 1:1000

Anti-Acetyl-CoA Carboxylase 1 antibody [RM232] used in IHC (Paraffin sections) (IHC-P). GTX33608

GTX33608 IHC-P Image

IHC-P analysis of human heart tissue using GTX33608 Acetyl-CoA Carboxylase 1 antibody [RM232].
Dilution : 1:300

REFERENCE

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REVIEW

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