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Acinus antibody

Anti-Acinus antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX27352
Anti-Acinus antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX27352
Anti-Acinus antibody used in Western Blot (WB). GTX27352

Cat. No. GTX27352

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, ELISA

Reactivity

 Human
Package
100 μg ($479)
See all Acinus products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-10μg/ml
ICC/IF 10μg/ml
ELISA Assay dependent
Not tested in other applications.

Calculated MW

152 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide corresponding to aa 1065-1080 of human AcinusL, aa 307-322 of human Acinus S and aa 338-353 of human AcinusS’ which are identical to those of mouse Acinus. These sequences are located near the C-terminus of the cleaved active peptide p17.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ACIN1 , ACINUS , ACN , apoptotic chromatin condensation inducer 1 , fSAP152 , Acinus

Cellular Localization

Nucleus,Nucleus speckle,Nucleoplasm

Background

Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Database

Research Area

DATA IMAGES

Anti-Acinus antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX27352

GTX27352 ICC/IF Image

ICC/IF analysis of K562 cells using GTX27352 Acinus antibody.
Green : Primary antibody
Blue : DAPI
Dilution : 20 μg/ml

Anti-Acinus antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX27352

GTX27352 ICC/IF Image

Immunocytochemical staining of K562 erythromyeloblastoid cells with rabbit anti Human Acinus (GTX27352)

Anti-Acinus antibody used in Western Blot (WB). GTX27352

GTX27352 WB Image

Western blot analysis of Acinus in K562 whole cell lysate with GTX27352

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 479