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Acinus antibody

Anti-Acinus antibody used in Western Blot (WB). GTX70370

Cat. No. GTX70370

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μg ($399)
See all Acinus products

APPLICATION

Application Note

For WB: Use at a dilution on 1:500-1:1,000. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

152 kDa. ( Note )

Product Note

C terminus of Acinus.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Immunogen sequence information is commercially sensitive and details are not available.

Purification

Affinity purified IgG

Conjugation

Unconjugated

RRID

AB_383242

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

apoptotic chromatin condensation inducer 1 , ACINUS , ACN , fSAP152

Cellular Localization

Nucleus , Nucleus speckle , nucleoplasm

Background

Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Database

Research Area

DATA IMAGES

Anti-Acinus antibody used in Western Blot (WB). GTX70370

GTX70370 WB Image

Western blot analysis of Acinus in transfected COS-7 cell lysate.

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399