A small molecule that acts as an antineoplastic antibiotic. Inhibits DNA-primed RNA polymerase by complexing with DNA via deoxyguanosine residues. A DNA-intercalator with growth inhibitory activity against certain leukemias and sarcomas. At higher concentrations, DNA polymerase is inhibited. Inhibits cell growth and colony formation in synchronized HeLa cells. A potent inducer of apoptosis in many cell lines
In DMSO (10 mM)
Store at -20ºC. Protect from light and moisture.
10 mM (Please refer to the vial label for the specific concentration.)
>98% pure, as determined by TLC
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Dactinomycin , Apoptosis Inducer , Actinomycin C1 , Actinomycin IV