APPLICATION
Application Note
For ELISA: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
GSS(n_octanoyl)FLSPEH
Purification
Affinity purified with antigen
Conjugation
Unconjugated
RRID
AB_625897
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
ghrelin and obestatin prepropeptide , MTLRP
Cellular Localization
Secreted
Background
This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression. [provided by RefSeq, Nov 2014]
Database
Research Area
DATA IMAGES
|
GTX78202 ELISA Image
GTX78202 in Sandwich ELISA for analysis of active ghrelin. Chicken anti-ghrelin C-terminal peptide (GTX78203) was coated on ELISA plate. Various concentrations of active ghrelin were incubated and detected with biotinylated GTX78202 at a 1:1000 dilution
|
REFERENCE
There are currently no references for Active Ghrelin antibody (GTX78202). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Active Ghrelin antibody (GTX78202). Be the first to share your experience with this product.
