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Activin Receptor Type IB antibody [11A7]

Anti-Activin Receptor Type IB antibody [11A7] used in IHC (Paraffin sections) (IHC-P). GTX52505

Cat. No. GTX52505

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 11A7

Isotype

 IgG1

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all Activin Receptor Type IB products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:100 - 1:1000
IHC-P 1:50
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

Product Note

This antibody was selected for its ability to detect human ALK4. No cross reactivity was found to ALK2 (Activin-R1A).

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant hu-ALK4 extra cellular domain

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ACTRIB , ACVR1B , ACVRLK4 , ALK4 , SKR2 , activin A receptor type 1B , Activin A receptor type IB

Cellular Localization

Cell membrane

Background

This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]

Database

  • Gene ID: 91 ACVR1B
  • UniProt: P36896 ACVR1B

Research Area

DATA IMAGES

Anti-Activin Receptor Type IB antibody [11A7] used in IHC (Paraffin sections) (IHC-P). GTX52505

GTX52505 IHC-P Image

IHC-P analysis of formalin fixed human placenta tissue using GTX52505 Activin Receptor Type IB antibody [11A7].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399