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Activin Receptor Type IB antibody [HL1266]

Recombinant antibody
Anti-Activin Receptor Type IB antibody [HL1266] used in Western Blot (WB). GTX636668
Anti-Activin Receptor Type IB antibody [HL1266] used in Western Blot (WB). GTX636668

Cat. No. GTX636668

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HL1266

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse
Package
100 μl ($399),
25 μl ($169)
See all Activin Receptor Type IB products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

Product Note

This antibody was raised against human Activin Receptor Type IB Intracellular domain.

Predict Reactivity

Rat, Pig, Xenopus tropicalis, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the Intracellular domain of human Activin Receptor Type IB. The exact sequence is proprietary.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

RRID

AB_2910036

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

activin A receptor type 1B , ACTRIB , ACVRLK4 , ALK4 , SKR2

Cellular Localization

Cell membrane

Background

This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]

Database

  • Gene ID: 91 ACVR1B
  • UniProt: P36896 ACVR1B

Research Area

DATA IMAGES

Anti-Activin Receptor Type IB antibody [HL1266] used in Western Blot (WB). GTX636668

GTX636668 WB Image

Various tissue extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Activin Receptor Type IB antibody [HL1266] (GTX636668) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

Anti-Activin Receptor Type IB antibody [HL1266] used in Western Blot (WB). GTX636668

GTX636668 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Activin Receptor Type IB antibody [HL1266] (GTX636668) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

REFERENCE

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REVIEW

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Package List Price ($)
$ 399
$ 169
Custom Conjugations