GeneTex
United States (US)

Activin Receptor Type IC antibody

GTX64969_20180530_IHC-P_5_18121411_907.jpg
GTX64969_20180530_IHC-P_1_18121411_252.jpg
GTX64969_20180530_WB_18121411_149.jpg
GTX64969_20180530_IHC-P_4_18121411_241.jpg
GTX64969_20180530_IHC-P_3_18121411_714.jpg
GTX64969_20180530_IHC-P_18121411_362.jpg
GTX64969_20180530_IHC-P_2_18121411_481.jpg

Cat No. GTX64969

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

55 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 22-113 of human ACVR1C (NP_660302.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

ALK7 Antibody , ACVRLK7 Antibody , ACVR1C Antibody

Background

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]

Database

Research Area

DATA IMAGES
GTX64969_20180530_IHC-P_5_18121411_907.jpg

GTX64969 IHC-P Image

IHC-P analysis of rat brain tissue using GTX64969 Activin A Receptor Type IC antibody.
Dilution : 1:100

GTX64969_20180530_IHC-P_1_18121411_252.jpg

GTX64969 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX64969 Activin A Receptor Type IC antibody.
Dilution : 1:100

GTX64969_20180530_WB_18121411_149.jpg

GTX64969 WB Image

WB analysis of SH-SY5Y cell lysates using GTX64969 Activin A Receptor Type IC antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX64969_20180530_IHC-P_4_18121411_241.jpg

GTX64969 IHC-P Image

IHC-P analysis of mouse stomach tissue using GTX64969 Activin A Receptor Type IC antibody.
Dilution : 1:100

GTX64969_20180530_IHC-P_3_18121411_714.jpg

GTX64969 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX64969 Activin A Receptor Type IC antibody.
Dilution : 1:100

GTX64969_20180530_IHC-P_18121411_362.jpg

GTX64969 IHC-P Image

IHC-P analysis of human stomach tissue using GTX64969 Activin A Receptor Type IC antibody.
Dilution : 1:100

GTX64969_20180530_IHC-P_2_18121411_481.jpg

GTX64969 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX64969 Activin A Receptor Type IC antibody.
Dilution : 1:100

Package List Price ($)
$ 319