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Activin Receptor Type IC antibody

Anti-Activin Receptor Type IC antibody used in IHC (Paraffin sections) (IHC-P). GTX64969
Anti-Activin Receptor Type IC antibody used in Western Blot (WB). GTX64969
Anti-Activin Receptor Type IC antibody used in IHC (Paraffin sections) (IHC-P). GTX64969
Anti-Activin Receptor Type IC antibody used in IHC (Paraffin sections) (IHC-P). GTX64969

Cat. No. GTX64969

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Activin Receptor Type IC products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

55 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 22-113 of human ACVR1C (NP_660302.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

activin A receptor type 1C , ACVRLK7 , ALK7

Cellular Localization

Membrane

Background

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]

Database

Research Area

DATA IMAGES

Anti-Activin Receptor Type IC antibody used in IHC (Paraffin sections) (IHC-P). GTX64969

GTX64969 IHC-P Image

IHC-P analysis of mouse stomach tissue using GTX64969 Activin Receptor Type IC antibody.
Dilution : 1:100

Anti-Activin Receptor Type IC antibody used in Western Blot (WB). GTX64969

GTX64969 WB Image

WB analysis of SH-SY5Y cell lysate using GTX64969 Activin Receptor Type IC antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Activin Receptor Type IC antibody used in IHC (Paraffin sections) (IHC-P). GTX64969

GTX64969 IHC-P Image

IHC-P analysis of human stomach tissue using GTX64969 Activin Receptor Type IC antibody.
Dilution : 1:100

Anti-Activin Receptor Type IC antibody used in IHC (Paraffin sections) (IHC-P). GTX64969

GTX64969 IHC-P Image

IHC-P analysis of rat brain tissue using GTX64969 Activin Receptor Type IC antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399