APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:5000-1:20000 |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse, Rat, Sheep, Bovine, Chicken, Pig, Xenopus tropicalis(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS, 20% Glycerol
Preservative
0.025% ProClin 300
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant protein encompassing a sequence within the Intracellular domain of human Activin A Receptor type IIA. The exact sequence is proprietary.
Purification
Purified by antigen-affinity chromatography.
Conjugation
Unconjugated
RRID
AB_2036159
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
activin A receptor type 2A , ACTRII , ACVR2
Cellular Localization
Membrane
Background
This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. [provided by RefSeq]
Database
-
Gene ID: 92
ACVR2A
-
UniProt: P27037
ACVR2A
Research Area
DATA IMAGES
![Anti-Activin Receptor Type IIA antibody [C1C3] used in Western Blot (WB). GTX114053](/templates/default/js/lightbox/images/loading.gif "Anti-Activin Receptor Type IIA antibody [C1C3] used in Western Blot (WB). GTX114053")
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GTX114053 WB Image
Activin A Receptor type IIA antibody detects Activin A Receptor type IIA protein by Western blot analysis. Whole cell extracts (30 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with Activin A Receptor type IIA antibody (GTX114053) diluted by 1:4000.
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REFERENCE
There are currently no references for Activin Receptor Type IIA antibody [C1C3] (GTX114053). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Activin Receptor Type IIA antibody [C1C3] (GTX114053). Be the first to share your experience with this product.
![Anti-Activin Receptor Type IIA antibody [C1C3] used in Western Blot (WB). GTX114053](/upload/website/prouct_img/small/GTX114053/GTX114053_41801_WB_w_23060501_128.webp "Anti-Activin Receptor Type IIA antibody [C1C3] used in Western Blot (WB). GTX114053")
![Anti-Activin Receptor Type IIA antibody [C1C3] used in Western Blot (WB). GTX114053](/upload/website/prouct_img/normal/GTX114053/GTX114053_41801_WB_w_23060501_128.webp "Anti-Activin Receptor Type IIA antibody [C1C3] used in Western Blot (WB). GTX114053")