GeneTex
United States (US)

Activin Receptor Type IIA antibody

GTX64724_20180530_IHC-P_3_18121411_169.jpg
GTX64724_20180530_IHC-P_18121411_418.jpg
GTX64724_20180530_IHC-P_6_18121411_993.jpg
GTX64724_20180530_IHC-P_4_18121411_709.jpg
GTX64724_20180530_IHC-P_7_18121411_922.jpg
GTX64724_20180530_WB_18121411_361.jpg
GTX64724_20180530_IHC-P_2_18121411_779.jpg
GTX64724_20180530_IHC-P_1_18121411_887.jpg
GTX64724_20180530_IHC-P_5_18121411_624.jpg

Cat No. GTX64724

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

58 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 20-140 of human ACVR2A (NP_001607.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

ACVR2 Antibody , ACVR2A Antibody , ACTRII Antibody

Background

This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013]

Database

DATA IMAGES
GTX64724_20180530_IHC-P_3_18121411_169.jpg

GTX64724 IHC-P Image

IHC-P analysis of human gastric cancer tissue using GTX64724 Activin Receptor type IIA antibody.
Dilution : 1:100

GTX64724_20180530_IHC-P_18121411_418.jpg

GTX64724 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX64724 Activin Receptor type IIA antibody.
Dilution : 1:100

GTX64724_20180530_IHC-P_6_18121411_993.jpg

GTX64724 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX64724 Activin Receptor type IIA antibody.
Dilution : 1:100

GTX64724_20180530_IHC-P_4_18121411_709.jpg

GTX64724 IHC-P Image

IHC-P analysis of human lung tissue using GTX64724 Activin Receptor type IIA antibody.
Dilution : 1:100

GTX64724_20180530_IHC-P_7_18121411_922.jpg

GTX64724 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX64724 Activin Receptor type IIA antibody.
Dilution : 1:100

GTX64724_20180530_WB_18121411_361.jpg

GTX64724 WB Image

WB analysis of various samples using GTX64724 Activin Receptor type IIA antibody.The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane

GTX64724_20180530_IHC-P_2_18121411_779.jpg

GTX64724 IHC-P Image

IHC-P analysis of human esophageal cancer tissue using GTX64724 Activin Receptor type IIA antibody.
Dilution : 1:100

GTX64724_20180530_IHC-P_1_18121411_887.jpg

GTX64724 IHC-P Image

IHC-P analysis of human colon tissue using GTX64724 Activin Receptor type IIA antibody.
Dilution : 1:100

GTX64724_20180530_IHC-P_5_18121411_624.jpg

GTX64724 IHC-P Image

IHC-P analysis of human stomach tissue using GTX64724 Activin Receptor type IIA antibody.
Dilution : 1:100

Package List Price ($)
$ 319