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Activin Receptor Type IIA antibody

Anti-Activin Receptor Type IIA antibody used in Western Blot (WB). GTX64724
Anti-Activin Receptor Type IIA antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64724
Anti-Activin Receptor Type IIA antibody used in IHC (Paraffin sections) (IHC-P). GTX64724
Anti-Activin Receptor Type IIA antibody used in IHC (Paraffin sections) (IHC-P). GTX64724
Anti-Activin Receptor Type IIA antibody used in IHC (Paraffin sections) (IHC-P). GTX64724

Cat. No. GTX64724

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Activin Receptor Type IIA products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 20-140 of human ACVR2A (NP_001607.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

activin A receptor type 2A , ACTRII , ACVR2

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013]

Database

  • Gene ID: 92 ACVR2A
  • UniProt: P27037 ACVR2A

Research Area

DATA IMAGES

Anti-Activin Receptor Type IIA antibody used in Western Blot (WB). GTX64724

GTX64724 WB Image

WB analysis of various sample lysates using GTX64724 Activin Receptor Type IIA antibody. The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Activin Receptor Type IIA antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64724

GTX64724 ICC/IF Image

ICC/IF analysis of A431 cells using GTX64724 Activin Receptor Type IIA antibody.
Blue : DAPI
Dilution : 1:100

Anti-Activin Receptor Type IIA antibody used in IHC (Paraffin sections) (IHC-P). GTX64724

GTX64724 IHC-P Image

IHC-P analysis of human esophageal cancer tissue using GTX64724 Activin Receptor Type IIA antibody.
Dilution : 1:100

Anti-Activin Receptor Type IIA antibody used in IHC (Paraffin sections) (IHC-P). GTX64724

GTX64724 IHC-P Image

IHC-P analysis of human lung tissue using GTX64724 Activin Receptor Type IIA antibody.
Dilution : 1:100

Anti-Activin Receptor Type IIA antibody used in IHC (Paraffin sections) (IHC-P). GTX64724

GTX64724 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX64724 Activin Receptor Type IIA antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399