GeneTex

  • Country / Location Selection

United States (US)

Adenylate cyclase 6 antibody

Anti-Adenylate cyclase 6 antibody used in IHC (Paraffin sections) (IHC-P). GTX47798
Anti-Adenylate cyclase 6 antibody used in Western Blot (WB). GTX47798
Anti-Adenylate cyclase 6 antibody used in IHC (Paraffin sections) (IHC-P). GTX47798

Cat. No. GTX47798

Reference 4

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IP, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($429)
See all Adenylate cyclase 6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:100-1:200
ICC/IF 1:10000
IHC-P Assay dependent
IP Assay dependent
ELISA 1:10000
Not tested in other applications.

Calculated MW

131 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tris/Glycine, 0.5% BSA, 30% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.59 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Synthetic peptide corresponding to N-terminal amino acids 13-27 of rat Particulate Adenylyl Cyclase 6 protein. Peptide was covalently modified and conjugated to KLH. Sequence:DERKTAWGERNGQKR

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_11177344

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

adenylate cyclase 6 , AC6 , ACVI , ADCYB

Cellular Localization

Cell membrane

Background

may play a role in intracellular signaling [RGD, Feb 2006]

Database

Research Area

DATA IMAGES

Anti-Adenylate cyclase 6 antibody used in IHC (Paraffin sections) (IHC-P). GTX47798

GTX47798 IHC-P Image

IHC-P analysis of rat heart tissue using GTX47798 Adenylate cyclase 6 antibody.
Dilution : 1:100

Anti-Adenylate cyclase 6 antibody used in Western Blot (WB). GTX47798

GTX47798 WB Image

WB analysis of ADCY6 recombinant protein using GTX47798 Adenylate cyclase 6 antibody.
Dilution : 1:500

Anti-Adenylate cyclase 6 antibody used in IHC (Paraffin sections) (IHC-P). GTX47798

GTX47798 IHC-P Image

IHC-P analysis of rat heart tissue using GTX47798 Adenylate cyclase 6 antibody.
Dilution : 1:100

REFERENCE

Application Reference

Yanda MK et al. Cell Signal 2018; 53 : 140-150 Role of calcium in adult onset polycystic kidney disease.
Yanda M et al. J Biol Chem 2018; (Epub) A potential strategy for reducing cysts in autosomal dominant polycystic kidney disease with a CFTR corrector.
Yanda MK et al. J Biol Chem 2017; (Epub) Histone deacetylase 6 Inhibition reduces cysts by decreasing via cAMP and Ca2+ in knockout mouse models of polycystic kidney disease.
Reactivity : Mouse
Yanda MK et al. Am J Physiol Renal Physiol 2017; : ajprenal.00186.2017 AN INHIBITOR OF HISTONE DEACETYLASE 6 ACTIVITY, ACY-1215, REDUCES cAMP and CYST GROWTH IN POLYCYSTIC KIDNEY DISEASE.
Submit a Reference

REVIEW

There are currently no reviews for Adenylate cyclase 6 antibody (GTX47798). Be the first to share your experience with this product.
Submit a Review
Package List Price ($)
$ 429