GeneTex
United States (US)

Aggrecan antibody [7D4]

GTX31216_69_WB_18121410_280.jpg

Cat No. GTX31216

Host Mouse
Clonality Monoclonal
Clone Name 7D4
Isotype IgG1
Application WB, IHC-P, IHC-Fr, IP, ELISA
Reactivity Human, Bovine
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P Assay dependent
IHC-Fr Assay dependent
IP Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

250 kDa. ( Note )

Specificity/Sensitivity

Mouse anti Human Aggrecan antibody, clone 7D4 recognizes epitopes within the N-terminal G1-IGD-G2 region of aggrecan, that has been identified as a cluster 1 isoform.
PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified human articular cartilage aggrecan

Purification

Protein A purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Aggrecan,Agc1,Agcan,Cspg1,Cspgcp,Msk16,Sedk,Ssoaod,Acan

Background

This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX31216_69_WB_18121410_280.jpg

GTX31216 WB Image

WB analysis of human aggrecan recombinant protein using GTX31216 Aggrecan antibody [7D4].

Package List Price ($)
$ 319