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Agrin antibody

Anti-Agrin antibody used in Western Blot (WB). GTX54904

Cat. No. GTX54904

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Agrin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

217 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol

Preservative

0.01% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of Agrin. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

agrin , AGRIN , CMS8 , CMSPPD

Cellular Localization

Cell membrane

Background

This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]

Database

Research Area

DATA IMAGES

Anti-Agrin antibody used in Western Blot (WB). GTX54904

GTX54904 WB Image

WB analysis of HEK293T (A), NIH3T3 (B), PC12 (C) whole cell lysates using GTX54904 Agrin antibody.

REFERENCE

Application Reference

Katie L Skeffington et al. Front Cardiovasc Med 2022; 9 : 813904 Determination of Agrin and Related Proteins Levels as a Function of Age in Human Hearts.
Application : IHC-P
Reactivity : Human
Guillaume Dumas et al. J Pineal Res 2021; 70 (3) : e12713 Mass-spectrometry analysis of the human pineal proteome during night and day and in autism.
Application : WB
Reactivity : Human
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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399