GeneTex
United States (US)

Alcohol Dehydrogenase antibody [1E5]

Cat No. GTX28335

Host Mouse
Clonality Monoclonal
Clone Name 1E5
Isotype IgG1
Application ICC/IF
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF Assay dependent
Not tested in other applications.

Calculated MW

39.86 kDa. ( Note )

Specificity/Sensitivity

This antibody reacts with ADH with Kd=10-10M This antibody does not influence oxidoreductase activity
PROPERTIES

Form

Liquid

Buffer

PBS pH 7.4, 0.1 % sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4º C.

Concentration

Batch dependent(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified alcohol dehydrogenase from human liver

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

ADH1, ADH1A, alcohol dehydrogenase 1A (class I), alpha polypeptide, Alcohol dehydrogenase 1A

Cellular Localization

Cytoplasm

Background

This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence. [provided by RefSeq, Nov 2010]

Database

Package List Price ($)
$ 219