Aldolase A antibody

Name: Aldolase A antibody
Brand: GeneTex
SKU: GTX37468
Price: 379.00 USD
Rating: 5 (1 reviews)

Anti-Aldolase A antibody used in IHC (Paraffin sections) (IHC-P). GTX37468

Cat No. GTX37468

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P
Reactivity	Human, Turtle
Package	100 μg ($379)

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	Assay dependent
IHC-P	1:400-800

Not tested in other applications.

Calculated MW

39 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.01M TBS pH7.4, 0.5% BSA, 25% Glycerol

Preservative

0.015% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 271-354 amino acids of human Aldolase A

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_11172111

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

aldolase, fructose-bisphosphate A , ALDA , GSD12 , HEL-S-87p

Background

This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Sep 2017]

Database

Gene ID: 226 ALDOA
UniProt: P04075 ALDOA

Research Area

DATA IMAGES

GTX37468 IHC-P Image

IHC-P analysis of human rectal carcinoma tissue using GTX37468 Aldolase A antibody.

REFERENCE

Application Reference

Dawson NJ et al. PLoS One 2013; 8 (7) : e68830 Characterization of fructose-1,6-bisphosphate aldolase during anoxia in the tolerant turtle, Trachemys scripta elegans: an assessment of enzyme activity, expression and structure.

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