GeneTex
United States (US)

Alpha 2 Antiplasmin antibody, Internal

GTX88657_2197_WB_18121411_571.jpg
GTX88657_883_IHC-P_18121411_496.jpg

Cat No. GTX88657

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.3-1μg/ml
IHC-P 3-5μg/ml
ELISA Assay dependent

Note :

Human Liver shows spotty cytoplasm staining in hepatocytes.
Not tested in other applications.

Calculated MW

55 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88657-PEP).

Specificity/Sensitivity

This antibody is expected to recognise both reported isoforms (NP_000925.2; NP_001159393.1).
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Concentration

0.50mg/ml

Antigen Species

Human

Immunogen

Peptide with sequence C-KDFLQSLKGFPRGDK, from the internal region of the protein sequence according to NP_000925.2; NP_001159393.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

API Antibody , AAP Antibody , SERPINF2 Antibody , PLI Antibody , A2AP Antibody , ALPHA2PI Antibody

Background

This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
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Database

Research Area

DATA IMAGES
GTX88657_2197_WB_18121411_571.jpg

GTX88657 WB Image

WB analysis of human duodenum lysate using GTX88657 Alpha 2 Antiplasmin antibody, Internal.
Dilution : 0.1µg/ml
Loading : 35µg protein in RIPA buffer

GTX88657_883_IHC-P_18121411_496.jpg

GTX88657 IHC-P Image

IHC-P analysis of human liver using GTX88657 Alpha 2 Antiplasmin antibody, Internal.
Antigen retrieval : citrate buffer pH 6
Dilution : 3.8µg/ml