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Amylin antibody [R10/99]

Anti-Amylin antibody [R10/99] used in IHC (Paraffin sections) (IHC-P). GTX11022

Cat. No. GTX11022

Reference 3

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 R10/99

Isotype

 IgG1

Application

 ICC/IF, IHC-P, IHC-Fr

Reactivity

 Human, Mouse
Package
1 ml ($429)
See all Amylin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-P 1/100
IHC-Fr 1/100

Note :

IHC-P
This product does not require protein digestion pre-treatment of paraffin sections.
Not tested in other applications.

Calculated MW

10 kDa. ( Note )

Product Note

This antibody recognizes the islet amyloid polypeptide (amylin).

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

A peptide CATQRLANFLV corresponding to residues 40-50 of human amylin coupled to tuberculin

Purification

Tissue Culture Supernatant

Conjugation

Unconjugated

RRID

AB_386073

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

islet amyloid polypeptide , DAP , IAP

Cellular Localization

Secreted

Background

This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity. [provided by RefSeq, Jul 2016]

Database

Research Area

DATA IMAGES

Anti-Amylin antibody [R10/99] used in IHC (Paraffin sections) (IHC-P). GTX11022

GTX11022 IHC-P Image

IHC-P analysis of human pancreas tissue using GTX11022 Amylin antibody [R10/99].

REFERENCE

Application Reference

Zheng Z et al. J Clin Invest 2019; 129 (8) : 3236-3251 CDKN2B upregulation prevents teratoma formation in multipotent fibromodulin-reprogrammed cells.
Hiroyuki Watanabe et al. Mol. Pharmaceutics 2018; 15 (12) : 5574-5584 Characterization of Novel 18F-Labeled Phenoxymethylpyridine Derivatives as Amylin Imaging Probes.
Application : IHC-P
Yoshimura M et al. Bioconjug Chem 2016; 27 (6) : 1532-9 Development of (99m)Tc-Labeled Pyridyl Benzofuran Derivatives To Detect Pancreatic Amylin in Islet Amyloid Model Mice.
Application : IHC-P
Reactivity : Mouse
Submit a Reference

REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 429