GeneTex

  • Country / Location Selection

United States (US)

Amyloid Precursor Protein peptide

Cat. No. GTX27874

Application

 Neutralizing/Inhibition

Species

 Human
Package
50 μg ($139)
See all beta Amyloid products

APPLICATION

Application Note

The peptide is used for blocking the activity of anti-APP. Incubatingthe peptide with equal volume of antibody for 30 min at 37ºC usually completely blocks theantibody activity in Western blotting.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.02% Sodium azide

Storage

Store the peptide at -20ºC, stable for one year.

Concentration

0.20 mg/ml (Please refer to the vial label for the specific concentration.)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Amyloid Beta Precursor Protein , Aaa , Abeta , Abpp , Ad1 , Appi , Ctfgamma , Cvap , Pn-Ii , Pn2 , Prea4 , App

Background

Amyloid Precursor Protein gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Research Area

REFERENCE

There are currently no references for Amyloid Precursor Protein peptide (GTX27874). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for Amyloid Precursor Protein peptide (GTX27874). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 139