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Androgen Receptor antibody [GT1228]

Recombinant antibody
Anti-Androgen Receptor antibody [GT1228] used in Western Blot (WB). GTX01536
Anti-Androgen Receptor antibody [GT1228] used in Western Blot (WB). GTX01536
Anti-Androgen Receptor antibody [GT1228] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX01536
Anti-Androgen Receptor antibody [GT1228] used in IHC (Paraffin sections) (IHC-P). GTX01536

Cat No. GTX01536

Host

Rabbit

Clonality

Monoclonal

Clone Name

GT1228

Isotype

IgG

Application

WB, ICC/IF, IHC-P

Reactivity

Human, Mouse
Package
100 μl ($379)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

99 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (pH7.3), 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human Androgen Receptor.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

AIS,AR,AR8,DHTR,HUMARA,HYSP1,KD,NR3C4,SBMA,SMAX1,TFM,androgen receptor,Androgen Receptor

Cellular Localization

Nucleus,Cytoplasm

Background

The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (SBMA, also known as Kennedy's disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2017]

Database

Research Area

DATA IMAGES

Anti-Androgen Receptor antibody [GT1228] used in Western Blot (WB). GTX01536

GTX01536 WB Image

Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Androgen Receptor antibody [GT1228] (GTX01536) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
The observed M.W. is based on the publication: PMID: 11306464

Anti-Androgen Receptor antibody [GT1228] used in Western Blot (WB). GTX01536

GTX01536 WB Image

WB analysis of mouse testis tissue lysate using GTX01536 Androgen Receptor antibody [GT1228].
Dilution : 1:1000
Loading : 25 μg

Anti-Androgen Receptor antibody [GT1228] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX01536

GTX01536 ICC/IF Image

ICC/IF analysis of LNCaP cells using GTX01536 Androgen Receptor antibody [GT1228].
Blue : DAPI

Anti-Androgen Receptor antibody [GT1228] used in IHC (Paraffin sections) (IHC-P). GTX01536

GTX01536 IHC-P Image

IHC-P analysis of human breast tissue section using GTX01536 Androgen Receptor antibody [GT1228].
Dilution : 1:100

REFERENCE

There are currently no references for Androgen Receptor antibody [GT1228] (GTX01536). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Androgen Receptor antibody [GT1228] (GTX01536). Be the first to share your experience with this product.
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 379