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Annexin II antibody

Anti-Annexin II antibody used in Western Blot (WB). GTX22242

Cat. No. GTX22242

Reference 3

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, ELISA

Reactivity

 Human, Mouse, Rat, Bovine, Pig
Package
50 μg ($399)
See all Annexin II products

APPLICATION

Application Note

Western Blot - Approx 35kDa band observed in wb.Recommended concentration: 0.5-3μg/ml.

Calculated MW

39 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence STVHEILCKLSLEGD, from N Terminus of the protein sequence according to NP_004030

Purification

IgG fraction
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Conjugation

Unconjugated

RRID

AB_367681

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

annexin A2 , ANX2 , ANX2L4 , CAL1H , HEL-S-270 , LIP2 , LPC2 , LPC2D , P36 , PAP-IV

Background

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Annexin II antibody used in Western Blot (WB). GTX22242

GTX22242 WB Image

Western blot analysis of Annexin II in A431 lysate (RIPA buffer, 35μg total protein per lane) using GTX22242 at 0.5μg/ml

REFERENCE

Application Reference

Daquinag AC et al. JCI Insight 2021; 6 (17) Fatty acid mobilization from adipose tissue is mediated by CD36 posttranslational modifications and intracellular trafficking.
Application : ICC/IF
Reactivity : Human
Jung H et al. Cell Death Dis 2015; 6 : e1606 intracellular annexin a2 regulates nf-κb signaling by binding to the p50 subunit: implications for * resistance in pancreatic cancer.
Application : WB, ICC/IF
Reactivity : Human
Sun Y et al. Carcinogenesis 2013; 34 (3) : 595-604 Annexin A2 is a discriminative serological candidate in early hepatocellular carcinoma.
Application : ELISA
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Package List Price ($)
$ 399